Retrograde Transport Redux

The Redux 0 Server

Redux 0 is a subset of the full REDUX modell7]. The latter performs problem solving. In contrast Redux 0 does not and acts only as a decision maintenance server. It takes objects of types deened in an ontology of decision components and maintains dependencies between them. Redux 0 is domain-independent. The dependency relationships are maintained on the basis of proposition type and not content...

Rubber gloves redux.

Mycalolide B dissociates dynactin and abolishes retrograde axonal transport of dense-core vesicles

Axonal transport is critical for maintaining synaptic transmission. Of interest, anterograde and retrograde axonal transport appear to be interdependent, as perturbing one directional motor often impairs movement in the opposite direction. Here live imaging of Drosophila and hippocampal neuron dense-core vesicles (DCVs) containing a neuropeptide or brain-derived neurotrophic factor shows that t...

Post-Golgi anterograde transport requires GARP-dependent endosome-to-TGN retrograde transport

The importance of endosome-to-trans-Golgi network (TGN) retrograde transport in the anterograde transport of proteins is unclear. In this study, genome-wide screening of the factors necessary for efficient anterograde protein transport in human haploid cells identified subunits of the Golgi-associated retrograde protein (GARP) complex, a tethering factor involved in endosome-to-TGN transport. K...

Rural Europe Redux

Rural Europe Redux? Reflections on Alternative Agro-Food Networks and Paradigm Change David Goodman Department of Environmental Studies University of California, Santa Cruz **Forthcoming in Sociologia Ruralis (2004), 44 (1)**